Life Sciences, Pharma & BioProcess
Measurement solutions for clinical, industrial and research applications.
Clinical Research and Diagnostics
Xylem analyzers measure glucose in blood, plasma, and serum; and lactate in blood, plasma, and cerebrospinal fluid. They are used extensively for glucose measurement in diabetes research and glucometer manufacturing settings; and for lactate in exercise physiology and athlete training programs. Our complete line of refractometers serve the sports science industry to ensure athletes receive optimum levels of hydration during training and competitions.
Food & Beverage
Our instruments measure common parameters like temperature, pH and key ingredients and byproducts in process settings and in quality assurance laboratories. Among the analytes are glucose, sucrose, lactose, starch, choline, glutamate and ethanol. In food spoilage applications lactate and ethanol levels provide quantitative evidence of unwanted microbes. Our biosensor technology is utilized from raw material analysis through final product QC testing and effluent monitoring. Our systems also test for a variety of contaminants that can be found in food such as benzene, herbicides, dyes, pesticides etc. Laboratory refractometers allow for precise measurement of concentration in the food and beverage industry.
We measure important nutrients like glucose, glutamine, and methanol; and can monitor the level of potentially harmful byproducts like lactate and ammonium. The biopharma industry uses Xylem’s rapid electrode-based measurements to both monitor and control processes.
Xylem analyzers measure xylose and glucose to monitor fermentation progress in cellulosic ethanol research and measure residual ethanol during distillation in production facilities.
Our analyzers measure key analytes. Results provide information related to growth factors, metabolism, toxic agents, and more.
Online Monitoring & Control
Xylem offers several products for online monitoring and control of key analytes in cell culture bioreactors. Our online monitoring & control systems offer a cost-effective, simple method for monitoring (with the possible addition of a feed pump/control).
Pharmaceutical water treatment – purity and sustainability are essential
From feedwater, through internal treatment to generate pharmaceutical grade water, to final discharge, water is critical to pharmaceutical manufacturing. Water treatment at each phase of manufacture must accomplish two goals: purity and sustainability. Contamination is potentially life threatening, so preventing water contamination is essential for product safety. Treatments must meet the standards of the relevant pharmacopeias for the intended use of the water, with different pharmaceutical grades requiring different treatments from purified water (PW) to highly purified water (HPW) to the highest purity of water for injection (WFI). Pharmaceutical manufacturers are also taking a proactive approach to sustainability, as both water scarcity and mitigation of environmental impacts encourage water efficiency through internal recycle and advanced treatment for final discharges.
While noting that treatment requirements vary depending upon the relevant pharmacopoeia, most treatment trains to generate purified water or WFI involve membranes (UF and/or RO), deionization, and/or distillation, and disinfection. However, treatments like thermal disinfection and distillation consume a lot of energy. Therefore, improving water efficiencies to reduce the quantity requiring treatment also improves energy efficiency. Internal reuse as wash water also reduces discharge volumes and wastewater treatment costs.
Because disinfection is so critical, multiple methods, including thermal, UV and ozonation, are typically employed at multiple points throughout the treatment process. These disinfection processes do not create chemical by-products, though use of ozone also requires equipment to destroy the ozone. UV is becoming the preferred process, but it only sanitizes at the point of application and does not address microbial biofilms that may accumulate in piping. To kill these biofilms, a residual type of disinfectant, typically ozone, must be periodically run through the treatment system.
Ozone, coupled with peroxide, and/or UV, is extremely effective in oxidizing microbial biofilms and bacteria. Xylem’s Wedeco brand is a trusted leader in proven sanitizing processes, providing both UV and advanced oxidation units involving ozone and peroxide. Wedeco’s UV systems lead the industry in energy efficiency, and the MiPRO series of advanced oxidation (ozone, peroxide and UV) units use a multipronged approach to provide the highest level of sanitation available.